Wolff (2015)
Quality Index (Adjusted QI) 0.711
0 Low < 0.56 Moderate 0.56–0.77 High ≥ 0.78 1
Study Details
ConditionHypertension + metabolic risk
Clinical domainCardiovascular
PopulationHigh CV risk primary care
Sample sizen = 83
Country / SettingSweden - cardiovascular risk population
Protocol clusterMediYoga
Duration12 weeks, 15 min 2x/day
Control typeUsual Care
ComparatorUsual care
Outcomes & Effect Sizes
Primary outcomeCardiovascular (BP/HRV)
Scales usedBP; CRP; IL-6; metabolic markers
Key resultInflammation biomarkers decreased; metabolic risk decreased
Effect sized = 0.35 (inflammatory markers); small effect
ES value0.35 (d)
Retention88% adherence maintained
SafetyNo adverse events; improved metabolic health
Methodological Summary
Randomized; biomarker outcomes; medium sample
KY Protocol Components
Kundalini Yoga for Hypertension — Inflammatory/Metabolic Biomarkers DESIGN: Same cohort as Wolff 2013 (N=83, 3 groups); 12-week intervention. OUTCOMES: Inflammatory biomarkers (hs-CRP, IL-6) and metabolic risk factors (FP-glucose, HbA1c, cholesterol, TG, LDL, HDL), BMI, waist circumference, WHOQOL-BREF. RESULTS: No evidence that yoga altered inflammatory biomarkers or metabolic risk factors. 49 participants (59%) met criteria for metabolic syndrome. NOTE: Same protocol as Wolff 2013. This paper focuses on biomarker outcomes (negative result) rather than BP or QoL. Published in BMC Cardiovasc Disord.
Quality Item Scores — 1 fail · 2 partial · 3 pass · ★ critical
★A1
3
A2
3
★B1
2
★B2
3
B3
3
B4
1
★B5
1
B6
2
★B7
2
★B8
3
B9
2
★C1
2
C2
1
C3
1
JP1
3
Critical fails1
Raw QI0.711
SAF1
Adjusted QI0.711
Final ratingModerate