Shannahoff-Khalsa (2019)

High · RCT · Clinical-Grade RCT · n = 52
Quality Index (Adjusted QI) 0.889
0 Low < 0.56 Moderate 0.56–0.77 High ≥ 0.78 1
Study Details
ConditionOCD (treatment-resistant)
Clinical domainOCD
PopulationAdults with OCD
Sample sizen = 52
Country / SettingUSA - psychiatric treatment settings
Protocol clusterOCD Protocol (Shannahoff-Khalsa)
DurationDaily 60-90 min intensive protocol
Control typeActive Control
ComparatorRelaxation Response
Outcomes & Effect Sizes
Primary outcomeOCD symptoms
Scales usedY-BOCS; CGI; treatment-resistant criteria
Key resultOCD decreased; treatment-resistant cases responded; sustained gains maintained
Effect sized = 0.98 (Y-BOCS); large effect; treatment-resistant responders
ES value0.98 (d)
Retention56% (27/48 Phase 1)” OR KY: 67% (16/24), RR: 46% (11/24)
SafetyNo serious adverse events; sustained gains maintained
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Methodological Summary

Randomized; replication/extension; medium-large sample

KY Protocol Components

OCD-Specific Kundalini Yoga Protocol: 11-technique meditation therapy with daily practice. CORE COMPONENTS: 8 primary daily techniques + 3 additional as-needed techniques KEY TECHNIQUE: Left-nostril breathing meditation (Unilateral Forced Nostril Breathing - UFNB) - cornerstone for OCD OTHER TECHNIQUES: For managing fear, phobias, anger, mental challenges, depression/anxiety PROTOCOL REFERENCES: Extensively documented in Shannahoff-Khalsa (1997) chapter "Yogic Techniques in Treatment of OCD" (pp. 283-329) and multiple CNS Spectrums publications STUDY-SPECIFIC: Recent RCT vs Relaxation Response; 38.4% Y-BOCS improvement at 3 months, 70.1% at 15 months (vs 13.9% control); published Front Psychiatry.

Quality Item Scores — 1 fail · 2 partial · 3 pass · ★ critical
★A1
3
A2
3
★B1
3
★B2
2
B3
3
B4
3
★B5
3
B6
3
★B7
2
★B8
3
B9
3
★C1
2
C2
2
C3
2
JP1
3
Critical fails0
Raw QI0.889
SAF1
Adjusted QI0.889
Final ratingHigh