Newberg (2010)

Moderate · Mechanism/Methods Study · Mechanism (Neuroimaging/Biomarker) · n = 15
Quality Index (Adjusted QI) 0.729
0 Low < 0.56 Moderate 0.56–0.77 High ≥ 0.78 1
Study Details
ConditionMemory loss
Clinical domainCognition & Neurodegeneration
PopulationPatients with memory loss
Sample sizen = 15
Country / SettingUSA - academic medical center (neuroimaging)
Protocol clusterKirtan Kriya (12-min)
Duration8 weeks, 12 min/day Kirtan Kriya
Control typeOther/Mixed
ComparatorN/A - Mechanism study
Outcomes & Effect Sizes
Primary outcomeBrain function (fMRI/SPECT/PET)
Scales usedSPECT imaging; CBF; cognitive testing; GDS
Key resultCerebral blood flow increased; memory improved
Effect sizeRegional cerebral blood flow increases; SPECT quantification
Retention100% (15/15 completed)
SafetyNo adverse events during imaging protocol
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Methodological Summary

Pre-post design; neuroimaging outcome; small sample; no control

KY Protocol Components

Kirtan Kriya: 12-minute singing meditation using mantra "Sa-Ta-Na-Ma" with finger movements (thumb touches index, middle, ring, pinky sequentially). Structure: 2 min aloud → 2 min whisper → 4 min silent → 2 min whisper → 2 min aloud. STUDY-SPECIFIC: Cerebral blood flow imaging study; neural correlates during practice vs relaxation control.

Quality Item Scores — 1 fail · 2 partial · 3 pass · ★ critical
★A1
3
A2
3
★B2
2
B3
3
B4
2
★B5
3
B6
2
★B7
2
★B8
1
B9
2
JP1
3
Critical fails1
Raw QI0.788
SAF0.925
Adjusted QI0.729
Final ratingModerate